EGFR

EGFR

EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

 

Alternative names: ERBB1; HER1; Epidermal Growth Factor Receptor

Product Name: Anti-EGFR Antibody
Reference #: CE00021
Clone #: UMAB95
Source #: Mouse Monoclonal
Reactivity: Human
Catalog Number &
Aliquote Size #:
C0044MA01-MA | 0.1 mL
C0044MA05-MA | 0.5 mL

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