Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq].
Alternative names: ARG1; OTTHUMP00000017209; Arginase 1; liver-type arginase; type I arginase; arginase, liver.
|Product Name:||Anti-ARG1 Antibody|
|Source #:||Mouse Monoclonal|