This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases [provided by RefSeq, Jul].
Alternative names: CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
| Product Name: | Anti-PD-1 Antibody |
|---|---|
| Reference #: | CE00059 |
| Clone #: | UMAB198 |
| Source #: | Mouse Monoclonal |
| Reactivity: | Human |
| Catalog Number & Aliquote Size #: |
C0059MA01-MA | 0.1 mL C0059MA05-MA | 0.5 mL C0059MA10-MA | 1.0 mL |
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