This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].
Alternative names: AMACRD; CBAS4; RACE; RM
| Product Name: | Anti-AMACR Antibody |
|---|---|
| Reference #: | CE00031 |
| Clone #: | UMAB68 |
| Source #: | Mouse Monoclonal |
| Reactivity: | Human |
| Catalog Number & Aliquote Size #: |
C0031MA01-MA | 0.1 mL C0031MA05-MA | 0.5 mL C0031MA10-MA | 1.0 mL |
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