Expressed by the MGMT gene, O6-methylguanine DNA methyltransferase repairs DNA by demethylating O6-methylguanine to guanosine. The O6-methylguanine causes errors during DNA replication and transcription by base-pairs to thymine rather than cytidine. MGMT methylation is associated with the loss of its protein expression. MGMT expression is variable in cancer tissues.

Alternative names: O6-alkylguanine DNA alkytransferase, AGT, AGAT

Product Name: Anti-MGMT Antibody
Reference #: CE00017
Clone #: UMAB56
Source #: Mouse Monoclonal
Reactivity: Human
Catalog Number &
Aliquote Size #:
C0017MA10-MA | 1.0 mL

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