Expressed by the MGMT gene, O6-methylguanine DNA methyltransferase repairs DNA by demethylating O6-methylguanine to guanosine. The O6-methylguanine causes errors during DNA replication and transcription by base-pairs to thymine rather than cytidine. MGMT methylation is associated with the loss of its protein expression. MGMT expression is variable in cancer tissues.
Alternative names: O6-alkylguanine DNA alkytransferase, AGT, AGAT
|Product Name:||Anti-MGMT Antibody|
|Source #:||Mouse Monoclonal|
|Catalog Number &
Aliquote Size #:
|C0017MA10-MA | 1.0 mL|
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