IDO1

IDO1

This gene encodes indoleamine 2,3-dioxygenase (IDO) – a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

Alternative names: IDO; IDO-1; INDO

Product Name: Anti-IDO1 Antibody
Reference #: CE00061
Clone #: UMAB126
Source #: Mouse Monoclonal
Reactivity: Human
Catalog Number &
Aliquote Size #:
C0061MA01-MA | 0.1 mL
C0061MA05-MA | 0.5 mL
C0061MA10-MA | 1.0 mL

Click the buttons below to download the corresponding PDF.

Coming Soon.

Other Products You May Like

Element

Become a Member


Continue

By continuing to use this site you agree to the use of cookies

SDIX uses cookies to improve your experience on the website and to provide you with services and content tailored to your interests

Learn more about The SDIX Cookie Policy

Learn more about The SDIX Privacy Policy

You have Successfully Subscribed!