BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008].
Alternative names: FP497
|Product Name:||Anti-BID Antibody|
|Source #:||Mouse Monoclonal|
|Catalog Number &
Aliquote Size #:
|C0030MA01-MA | 0.1 mL|
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