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AGC1 antibody

SEQer™ Antibodies - Successful results in complex assays

• Bioinformatic design which selects the optimal 100 amino acid residues for high specificity with low cross reactivity
• In-vivo expressed antigen which recognize protein's native conformation with multiple epitopes
• Excellent tools for immuno-precipitation, sandwich ELISA, antibody array, IF, immunohistochemistry, and more

Description 

Reactivity:	Human
Source:	Rabbit Polyclonal
Immunogen:	In vivo generated recombinant protein fragment
Purification:	Affinity purified using a recombinant protein fragment
QC Test:	QC tested by ELISA using a recombinant protein
Buffer:	20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Synonyms:	Aggrecan core protein antibody, AGC1 antibody, Aggrecan 1 antibody, Aggrecan structural proteoglycan of cartilage antibody, Cartilage specific proteoglycan core protein antibody, CSPCP antibody, Chondroitin sulfate proteoglycan core protein 1 antibody, CSPG1 antibody, JSCATE antibody, MSK 16 antibody, SEDK antibody.
Type:
Datasheet:

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Catolog #	Size	Price
3533.00.02	50 ug	Click for Price

Background Data 

GeneFunction:	This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
BelongsTo:
TissueLoc:	Restricted to cartilages.
SubCellLoc:	Secreted, extracellular space, extracellular matrix (By similarity).
DiseaseAssoc:	Defects in AGC1 are the cause of spondyloepiphyseal dysplasia type Kimberley (SEDK) [MIM:608361]. Spondyloepiphyseal dysplasias are a heterogeneous group of congenital chondrodysplasias that specifically affect epiphyses and vertebrae. The autosomal dominant SEDK is associated with premature degenerative arthropathy.
Pathway:
Topology:	Nonmembrane Protein