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ABCA3 antibody

SEQer™ Antibodies - Successful results in complex assays

  • Bioinformatic design which selects the optimal 100 amino acid residues for high specificity with low cross reactivity
  • In-vivo expressed antigen which recognize protein's native conformation with multiple epitopes
  • Excellent tools for immuno-precipitation, sandwich ELISA, antibody array, IF, immunohistochemistry, and more

SDIX's antibodies are exclusively distributed by Novus Biologicals.   Click the Purchase section below and "Add to Cart" below to be taken to Novus Biological's web site to complete your order.   Or call Novus Biologicals toll-free (888)506-6887, 9am-7:30pm EST.  

Description 

Reactivity: Human
Source: Rabbit Polyclonal
Immunogen: In vivo generated recombinant protein fragment
Purification: Affinity purified using a recombinant protein fragment
QC Test: QC tested by ELISA using a recombinant protein
Buffer: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Synonyms: ATP-binding cassette sub-family A member 3 antibody, ATP-binding cassette transporter 3 antibody, ATP-binding cassette 3 antibody, ABC-C transporter antibody, ABC3 antibody, mgc166979 antibody; lbm180 antibody; est111653 antibody; smdp3 antibody; mgc72201 antibody; ATP-binding cassette, sub-family A (ABC1), member 3 antibody.
Type: SeqAntibodies Icon
Datasheet:

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Catolog # Size Price  
3828.00.02 50 ug Click for Price Add to Cart

Background Data 

GeneFunction: Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
BelongsTo:
TissueLoc: Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
SubCellLoc:
DiseaseAssoc: Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3) [MIM:610921]; also called pulmonary alveolar proteinosis due to ABCA3 deficiency. Inborn errors of pulmonary surfactant metabolism are genetically heterogeneous disorders resulting in severe respiratory insufficiency or failure in full-term neonates or infants. These disorders are associated with various pathologic entities, including pulmonary alveolar proteinosis (PAP), desquamative interstitial pneumonitis (DIP), or cellular non-specific interstitial pneumonitis (NSIP).
Pathway:
Topology: Membrane Protein; Outside (predicted by TMHMM)