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Complement component 3 - C3

Description:

Goat Anti-human C3 – Polyclonal Antibody

Product Code:

S0511G000-S4

Source :

Goat

Antigen Source:    

Purified Human C3

Stage/Grade:

Serum and Fractionated

Storage:

2°C to 8°C

Buffer:

0.02M Sodium Phosphate, 0.15M Sodium Chloride, 0.1% NaN3 or other as specified

Test

Specification

Appearance:    

Amber and free from particulates

Final pH:

6.0-8.0

Reactivity:

Monospecific, precipitates with human C3

 

Product Specification:

The product is made by immunizing the host (goat) with purified Human C3; antiserum is defibrinated and delipidated, monospecificity is tested by IEP versus normal plasma and 2x concentrated human serum. Immunoturbidimetric reactivity is determined on Hitachi 911.

The product can be customized to various automated immunoassay platforms. Factors such as detection limit, sensitivity, linearity, and antigen excess (prozone) can be adjusted and controlled.

Product Availability: Immediate

Product Supply: mL to Multi-Liter Scale

C3 is a 1663 amino acid protein produced by hepatic parenchymal cells. It is required for the activation of classical (antigen - antibody based), alternative (non specific) and lectin pathways of complement systems. C3 is a central component of the immune system and people with C3 deficiency are more susceptible to bacterial infection. Measuring the C3 level, along with other complements, is useful to diagnose and monitor the activity of autoimmune disorders such as SLE.