News, How To's & Offers

Sign up to receive occasional emails from SDIX. We strive to deliver valuable information and savings to you.

Contact Us

Do you have questions? Want to place an order?

Bookmark and Share

Bioinformatics and Design

Antigen Choice Determines Immunoassay Success

Different immunoassays present the target protein in different structural states.  In general, immunoassays that require the target to have native epitopes are of higher value.

Denatured-vs-Discontinuous

Importance of Bioinformatics in Design

Consideration of which area of the protein to bind to is highly important for a successful antibody.  The following need to be considered:

  • Highly conserved regions

  • Paralogous regions

  • Interior/transmembrane regions

  • PTMs

  • Interaction sites

  • Splice variants

  • Topology

Fit For Purpose Antigens

Spectrum of choices to match requirements

Fit For Purpose Antigens

 

Learn more about SDIX's approach to antibodies designed to be highly specific and sensitive in our Expert Advice section.