SDIX collaborated with researchers using rhesus macaques as a model
organism for HIV research. In previous studies, the commercially
available anti-human CD40 antibody gave unreliable data in the macaque
model, even though the human protein sequence is 93% homologous.
Utilizing proprietary bioinformatic algorithms, SDIX’s scientists selected a 100 amino acid region of the rhesus CD40 protein to use as the target sequence for SDI’s proprietary Genomic Antibody Technology™.
Polyclonal mouse sera was delivered in 76 days. The antibody was highly successful in selective binding to rhesus B-cells in FACS analysis.
